Hybrid

Hybrids are a cross-breed of two or more supernatural species. The term is usually associated with vampire-werewolf hybrids. Or a werewolf who has turned into a vampire. But since their introduction in the first book, there has been more hybrids, such as a siphoner vampire-witch hybrid, witch-werewolf hybrid, and even in the unique case of Brandon Smith where he is a Lunar vampire-witch hybrid, even not being a siphoner. Also another unique case of Brandons son, Grayson Schwartz where he is a Quadbrid; when he was possessed by a powerful witch spirit, Christopher; he used very powerful dark magic to create the worlds first Quadbrid.

Hybrids have the combined strengths and some weaknesses of their parent races, along with powerful attributes unique to themselves alone due to their combined heritage. For werewolf-vampire hybrids, this includes day walking and being able to transform into a wolf without the Full Moon's influence. for a siphoner witch, they retain the ability to siphon magic from their own vampirism, and can use that newly siphoned magic on/as witchcraft, as they did not possess their own magic as humans, this is a skill that makes them powerful.

Werewolf-Vampire
Their origins are relatively unknown

Original Hybrid
There is only one of these hybrids living. Brandon Smith is an unknown wonder. Because vampires cannot be a witch and remain their power, because vampires are a mistake and go against the laws of nature. When Brandon was resurrected on July 11th, he created the lunar vampire curse. it is relatively unknown why Brandon became a hybrid, even before he became a lunar vampire, Brandon was a witch vampire hybrid. He was resurrected as a original vampire, but after Rebekah staked him, the lunar vampire curse was initiated, making him the original lunar vampire, and witch hybrid. a lunar vampire is stronger and faster than even an original vampire. A lunar vampire hybrid, is one of nature's most horrible creations. But, for almost every new strength that this new hybrid has, there came a weakness. Unlike most hybrids, Brandon had to wear a daylight amulet. (his was is the form of a ring). For Brandon's strength, it was hindered by his witchcraft. For every spell, it would drain his abilities. But he easily overcomes this by feeding. His lunar vampire bite, came with the weaknesses as well. He could only turn other vampires. He could not turn any humans. He would have to have one of his minions to turn, then he could turn them into a lunar vampire.

The Quadbrid
Main Article: Grayson Schwartz

When Grayson was born, he was created as one of Natures loopholes; not only is Grayson the son of one of the most powerful Hybrids in the world. Grayson other than his father's, is one of the only cures for a Lunar Vampire bite, a trait he inherited from his father. Grayson Schwartz was born as a siphon, however; if Grayson would have died (without vampire blood) he would have awoken as a hyrbid anyway.

Its been Proven that Graysons blood is a powerful biding agent; similar to Doppelgänger blood. This eliminates the need for doppelgänger blood during the transition, though only the quadbrids blood can finish the transition of a new hybrid, thus the hybrid race still depends on a single and rare supernatural creature. Since becoming a quadbrid, it is unclear if his blood can still create hybrids, similar to how Brandon's undead blood become useless to create new vampires, it is unknown if Graysons blood can create new vampires.

Known types of Hybrids

 * Original Vampire-Witch Hybrid- Brandon Smith (formally)
 * Original Lunar Vampire-Witch hybrid- Brandon Smith
 * Vampire-Werewolf Hybrid- Eleanor DeCatur
 * Vampire-Witch Hybrid- Grayson Schwartz (formally), Edward Herron
 * Original Lunar Vampire-Witch-Manticore-Leviathan Quadbrid-Grayson Schwartz

Werewolf-vampire:
Non-Original werewolf-vampire hybrids have the powers and abilities of both werewolves and non-Original vampires, both physically enhanced powers and abilities of mind compulsion. Non-Original werewolf-vampire hybrids will grow stronger with age due to their vampirism and will also increase in strength when enraged, due to their werewolf side. Their strength will also increase during a full moon.


 * Super Strength: Non-Original werewolf-vampire hybrids are stronger than Werewolves, Evolved Werewolves, non-Original Vampires, Supernatural Hunters, Immortals and Humans. Due to their vampire side, they also get stronger with age. The full moon will boost their strength and aggression. Older non-Original vampires may be stronger and more challenging for many newborn non-Original werewolf-vampire hybrids. However, if a non-Original werewolf-vampire hybrid fights a non-Original vampire closer to their age range, the non-Original werewolf-vampire hybrid will win


 * Super Speed: A non-Original werewolf-vampire hybrid's intensified quickness, agility, reflexes, and endurance makes them faster than any werewolves, evolved werewolves, non-Original vampires, supernatural hunters, immortals, and humans. Non-Original werewolf-vampire hybrids can use this ability in human or werewolf form. As with strength, non-Original werewolf-vampire hybrids get faster with time. The full moon will increase their speed and being in werewolf form will make them even faster. Tyler was particularly fast as a non-Original werewolf-vampire hybrid, being fast enough to surprise Klaus and stake him.


 * Super Agility: Non-Original werewolf-vampire hybrids possesses much more superhuman stamina, flexibility, reflexes, agility, and dexterity than immortals, non-Original vampires, werewolves, evolved werewolves and humans. They can move, jump, climb, and run incredibly fast without difficulty or exhaustion


 * Super Senses: Non-Original werewolf-vampire hybrids have extremely keen senses of hearing, sight, touch, and smell that exceed those of non-Original vampires, werewolves, evolved werewolves, and humans. Since they're a supernatural crossbreed between werewolves and non-Original vampires, non-Original werewolf-vampire hybrids have the combined senses of both species thus making their ability extremely effective


 * Super Durability: Non-Original werewolf-vampire hybrids can bear a lot of trauma. They also hardly ever get tired or fatigued. Non-Original werewolf-vampire hybrids can take far more trauma than any non-Original vampires, werewolves, evolved werewolves and humans, without much discomfort or injury. Stakes and arrows can not kill a non-Original werewolf-vampire hybrid when they are struck in the heart, they merely become unconscious


 * Enhanced Healing Factor: Non-Original werewolf-vampire hybrids have the combined healing capabilities of both non-Original vampires and werewolves, rendering them practically invincible to anything but fatal wounds that can seriously impair their healing capabilities like decapitation or heart-extraction. They can recover/heal/regenerate from any injury much quicker and more effectively than any non-Original vampires, werewolves, evolved werewolves, and humans. They also seem to heal much more quickly when exposed to vervain, wolfsbane, or wood. Human blood has also known to make the healing process faster.
 * Immortality: Non-Original werewolf-vampire hybrids stop aging the moment they transition. They become immune to all conventional diseases, toxins, poisons, viruses, illness, infections, and injuries.
 * Day Walking: Due to their werewolf heritage, non-Original werewolf-vampire hybrids are immune to the lethal effects that u.v. rays and sunlight have on non-Original vampires and original vampires. Allowing them to walk in daylight without the use of a day ring.
 * Emotional Control: Due to their vampire heritage, non-Original werewolf-vampire hybrids are able to exert certain control over their own emotions, e.g. They can turn off their humanity.
 * Enhanced Emotions: Because of their vampiric and werewolf traits, non-Original werewolf-vampire hybrids experience emotions more powerfully than humans and non-Original vampires. Particularly emotions such as anger, rage, aggression, and violence due to their werewolf heritage. Non-Original werewolf-vampire hybrids are more prone to violence and rage than non-Original vampires. However, emotions such as love, joy, and happiness are intensified for them as well, allowing them to live life more intensely. This ability allows them to feel emotions at their peak regardless of their age.
 * Lycanthrope Enhancement: Non-Original werewolf-vampire hybrids are capable of using their werewolf features to further supplement their powers and abilities. Non-Original werewolf-vampire hybrids can grow claws from their nails and werewolf fangs from their teeth even when they are still in their human forms.
 * Mind Compulsion: A non-Original werewolf-vampire hybrid can compel the minds of Humans. They cannot, however, compel original vampires, non-Original vampires, Supernatural Hunters, Witches or Werewolves
 * Shapeshifting/Transformation Control: Non-Original werewolf-vampire hybrids have the ability to transform into their werewolf forms at will. Most of them avoid transforming at all due to the pain it causes. They have complete awareness, but they still, however, have no control of their actions in werewolf form. They can also perform partial transformations, manifesting single features of their werewolf forms.


 * Werewolf Bite: Due to their werewolf heritage, non-Original werewolf-vampire hybrids and Klaus have venom which is fatal to non-Original vampires and they themselves are immune to werewolf venom. Non-Original werewolf-vampire hybrid venom seems to take effect much faster than a normal werewolf venom.
 * Immunity to Silver: Due to their werewolf heritage, magic bonded to silver doesn't affect non-Original werewolf-vampire hybrids. Weapons made of silver might wound them, but the wound heals at super-normal rates than regular wounds.

Lunar Vampire-witch hybrid
The hybridization of a witch and a vampire has long been thought to be impossible. But, somehow the addition of the lunar vampire curse, bypasses the rule. Somehow, the addition allows a witch to become a lunar vampire and still retain the ability to practice magic.


 * Super strength: Non-Original lunar vampire-witch hybrids are stronger than Werewolves, Evolved Werewolves, non-Original Vampires, Supernatural Hunters, Immortals and Humans. Due to their vampire side, they also get stronger with age. A lunar vampire is stronger than an original, depending how old the vampire is when they turn. A vampire like Nickolas Johnson who is over 1000 years old, is barley stronger than an original. They always have the advantage of superior strength in direct combat with a human. Their other feats include single-handedly lifting grown men high off the ground by the throat and snapping their necks, cutting off a person's head with their bare hands, and ripping out internal organs such as hearts with little to no effort. Their strength is also more powerful than that of Werewolves and Evolved Werewolves in human form. Their strength allows them to jump higher and further than any natural creature.


 * Super Speed: Non-Original lunar vampire-witch hybrids possess the same speed as non-Original vampires; able to accelerate their movements to cover short distances in an instant, faster than the human eye can see. When running across long distances, they appear as vibrating blurs of motion. Their reflexes are similarly heightened. Like their strength, their speed increases with age.


 * Super agility: Non-Original lunar vampire-witch hybrids possess superhuman agility. They have shown that they can move, jump very high, climb, and run incredibly fast without difficulty or exhaustion. They can jump with their super speed too. These abilities increase with age.


 * Super Senses: Non-Original lunar vampire-witch hybrids possess extremely keen senses of hearing, sight and smell that far exceed those of humans and werewolves.
 * Super Durability: Non-Original lunar vampire-witch hybrids can take a great amount of physical damage without being slowed down. Even vampires who have been shot with wooden bullets have been seen to continue fighting, as long as they were not shot in the heart, or the head. As they get older they become more powerful.
 * Healing Factor: Non-Original lunar vampire-witch hybrids possess the ability to recover tissue from any form of physical damage to their bodies in seconds, but still feel the pain of a wound before it heals. Vampires can snap their bones back into place after being broken and have been seen to fully recover from gunshots, stab wounds, and torso impalement.
 * Immortality: Non-Original lunar vampire-witch hybrids stop aging once turned. Upon their transformation, they become immune to all conventional illness, diseases, viruses and infections, though the exception is cancer, which can only be exacerbated by vampirism.
 * Spell Casting: Non-Original witch-lunar vampire hybrids possess the ability to cast spells like any witch.


 * Telekinesis: Non-Original witch-lunar vampire hybrids possess the ability to move objects and people with the mind like any witch.
 * Pain Infliction: Non-Original witch-lunar vampire hybrids possess the ability to inflict excruciating migraines like any witch.
 * Pyrokinesis: Non-Original witch-lunar vampire hybrids possess the ability to create and control fire like any witch.
 * Divination: Non-Original witch-lunar vampire hybrids possess the ability to divine future, past, and present events based off extrasensory perception like any witch.

Siphoner-vampire Hybrid
The hybridization of a witch and a vampire has long been thought to be impossible. However, a subsection of mutated witches with the ability to siphon magic known as siphoners have shown to bypass this rule. A group known as the Heretics consists of these hybrids.


 * Siphoning: Non-Original witch-vampire hybrids possess the rare ability to absorb magic, in all forms, from another source.
 * Spell Casting: Non-Original witch-vampire hybrids after having absorbed magic, possess the ability to cast spells like any witch.


 * Telekinesis: Non-Original witch-vampire hybrids after having absorbed magic, possess the ability to move objects and people with the mind like any witch.
 * Pain Infliction: Non-Original witch-vampire hybrids after having absorbed magic, possess the ability to inflict excruciating migraines like any witch.
 * Pyrokinesis: Non-Original witch-vampire hybrids after having absorbed magic, possess the ability to create and control fire like any witch.
 * Divination: Non-Original witch-vampire hybrids after having absorbed magic, possess the ability to divine future, past, and present events based off extrasensory perception like any witch.
 * Super Strength: Non-Original witch-vampire hybrids are stronger than non-Original vampires, Supernatural Hunters, Immortals and Humans and slowly grow stronger with time. They always have the advantage of superior strength in direct combat with a human. Their other feats include single-handedly lifting grown men high off the ground by the throat and snapping their necks, cutting off a person's head with their bare hands, and ripping out internal organs such as hearts with little to no effort. Their strength is also more powerful than that of Werewolves and Evolved Werewolves in human form. Their strength allows them to jump higher and further than any natural creature. Grayson was able to fight Andrew Blake a 600 year old vampire, on equal terms. Despite being a newly turned hybrid. Grayson was able to throw Andrew into a wall, and almost ripped out his heart. Hybrids such as Edward Herron, was able to fight off Katherine Catlyon ( an enhanced vampire), but this was mainly due to his ability to siphon her vampirism.
 * Super Speed: Non-Original witch-vampire are faster than non-Original vampires; able to accelerate their movements to cover short distances in an instant, faster than the human eye can see. When running across long distances, they appear as vibrating blurs of motion. Their reflexes are similarly heightened. Like their strength, their speed increases with age. Grayson Schwartz was incredibly faster than Annie Eress and was able to outrun her and kill her.
 * Super Agility: Non-Original witch-vampire hybrids possess superhuman agility. They have shown that they can move, jump very high, climb, and run incredibly fast without difficulty or exhaustion. They can jump with their super speed too. These abilities increase with age.
 * Super Senses: Non-Original witch-vampire hybrids possess extremely keen senses of hearing, sight and smell that far exceed those of humans and werewolves.
 * Super Durability: Non-Original witch-vampire hybrids can take a great amount of physical damage without being slowed down. Even vampires who have been shot with wooden bullets have been seen to continue fighting, as long as they were not shot in the heart, or the head. As they get older they become more powerful. Edward Herron was shown to have incredible durability, after being stabbed and punched multiple times by Katherine, and continuing to fight while still using his magic, to telekinetically throw her into the ceiling.
 * Healing Factor: Non-Original witch-vampire hybrids possess the ability to recover tissue from any form of physical damage to their bodies in seconds, but still feel the pain of a wound before it heals. Vampires can snap their bones back into place after being broken and have been seen to fully recover from gunshots, stab wounds, and torso impalement. Their healing is much faster than that of non-original lunar vampires.
 * Immortality: Non-Original witch-vampire hybrids stop aging once turned. Upon their transformation, they become immune to all conventional illness, diseases, viruses and infections, though the exception is cancer, which can only be exacerbated by vampirism. non-original witch vampire hybrids, cannot be killed by torso impalement, and gunshots.


 * Day Walking: Due to their Siphoner heritage, non-Original witch-vampire hybrids are be immune to the lethal effects that u.v. rays and sunlight have on non-Original vampires and original vampires. Allowing them to walk in daylight without the use of a daylight ring.
 * Enhanced Emotions: Non-Original witch-vampire hybrids experience emotions more powerfully than humans. Emotions like love, joy, and happiness are magnified for vampires, allowing them to live life more intensely.
 * Emotional Control: Non-Original witch-vampire hybrids have the supernatural ability to remove or dull their emotions by "turning off" or "switching off" their humanity which is directly connected to their emotions. Doing so allows them to block out their more negative emotions, such as fear and guilt, allowing them to feed and kill without remorse.


 * Mind Compulsion: Non-Original witch-vampire hybrids have the ability to influence and control thoughts, emotions, and behavior and can alter or erase memories.
 * Sire Bond: Although rare among them, sire bonds can be formed when a human is turned with the blood of the vampire whom they had strong human feelings for.
 * Telepathy: Non-Original witch-vampire hybrids have the ability, albeit a weak variant, to enter the minds of others as long as theirs is stronger than them. Normally, this ability works in a tactile fashion and the vampire requires physical contact in order for it to work successfully. Like their physical attributes, their mental strength increases with age.
 * Dream Manipulation: Non-Original witch-vampire hybrids can control dreams and subconscious. They can produce and modify dreams, bestow nightmares or lucid dreaming. Other effects of this ability is the distortion of reality and trapping people in their dream.
 * Illusions: Non-Original witch-vampire hybrids have the power to trick the minds of others into seeing/feeling things that aren't actually happening.

Original Lunar Vampire-witch hybrid:
Brandon has the powers of a original lunar vampire, and witch, both physically enhanced powers and abilities of mind compulsion. His strength and speed will also increase during a lunar eclipse. Brandon is slightly more physically powerful than his siblings.


 * Super Strength: Brandon is much stronger than immortals, Supernatural Hunters, non-Original vampires, werewolves, Evolved werewolves, non-Original werewolf-vampire hybrids and humans. He is able to decapitate other species with a single chop and shatter windows and doors with small objects. He is even slightly physically superior to the Original vampires, even more so when enraged, using his lunar enhancements due to his witch side. Mark, and Blake were able to fight Brandon on equal terms, but neither of them were able to defeat him. Brandon was able to fight off Rebekah, Jackson, Nadia, and Samantha with ease. Brandon is superior to all of them by both having original vampire boths, tied with the lunar upgrade, and his witch side. Brandon was also able to fight off 15 non-original vampires.


 * Super Speed: Brandons' intensified quickness, agility, reflexes, and endurance makes him much faster than immortals, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, supernatural hunters and humans, he is slightly faster than his Original Vampire siblings, as he once said, "I'm faster than your normal vampire, im enhanced". A lunar vampire is much faster than a non-original vampire. . He is able to stop other supernatural species in their tracks and run miles in mere minutes. His reflexes are similarly heightened, as he once caught Benjamins arm before the latter could stab him with a small stake; he later saved both himself and Benjamins from an explosion intentionally triggered by him.


 * Super Agility: Brandon possesses much more superhuman stamina, flexibility, reflexes, agility and dexterity than any immortals, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, and humans, even slightly more than original vampires. He can move, jump very high, flip, climb, and run incredibly fast without difficulty or exhaustion.
 * Super Senses: Brandon has a more enhanced sense of hearing, sight and smell that far exceeds those of any immortals, original vampires, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, and humans.
 * Super Durability: Brandon can take far more trauma than any immortals, original vampires, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids and humans, without much discomfort or injury. However, like with his siblings, he has never been dismembered throughout the series, implying that his durability may be close to invincibility though he can still be hurt. Wood and Red Oak Ash Daggers do not weaken him, making him virtually indestructible
 * Enhanced Healing Factor: The injuries of Brandon heal faster than those of supernatural hunters, Original vampires, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, and humans. He also seems to heal much more quickly when exposed to vervain, a huntresses blood, or wood. He can heal/recover/regenerate from any and all injuries in a matter of seconds. Vervain laced liquid has also been shown to weaken him, though he recovers from the effects much more quickly. Human blood has also known to make the healing process faster.
 * Immortality: Brandon is even more immortal than his siblings. With the last Red Oak Stake destroyed, no physical weapon on earth can kill him. Nothing but immense magical power worth a hundred witches summoned by an exceptionally powerful witch can kill Brandon. Despite the extent of his immortality, Brandon still needs to feed otherwise he will desiccate and become immobile just like any other immortals, Original vampires, non-Original vampires, or non-Original hybrids.


 * Lunar vampire Bite: Due to his lunar vampire heritage, Brandon has venom which is fatal to non-Original vampires and original vampires. Brandon himself is immune to the venom. Brandon' venom seems to take effect much faster than werewolf venom, a non-Original werewolf-vampire hybrid venom, and a non-original lunar vampire-witch venom. a lunar vampire bite can cause extreme amounts of pain and numbness. It is unknown if the venom can kill a hybrid, but as shown when Grayson was bitten by him he still felt the effects of the venom, but he wasn't killed due to the fact that he siphoned it away. The blood of a non-original lunar vampire will not cure the effects of the wound. But, their blood will slow down the poison. Giving the vampire more time.
 * Lunar Vampire Bite Cure: Brandons' blood is the only cure for a normal lunar vampire or a non-Original lunar vampire-witch hybrid venom, this ability seems to be unique only to Brandon. His blood will not cure a werewolf bite.
 * Spell casting: Brandon is able to cast spells, even as a vampire.
 * Telekinesis: Brandon possess the ability to move objects and people with the mind like any witch.
 * Pain Infliction: Brandon possess the ability to inflict excruciating migraines like any witch
 * Pyrokinesis: Brandon possess the ability to create and control fire like any witch.
 * Divination: Brandon possess the ability to divine future, past, and present events based off extrasensory perception like any witc
 * Projection: The power to separate from one's body and project the mind to another location or to instantaneously travel from one point to another.
 * Transmogrification: The unique power to alter the physical structure of objects living or dead, changing their form.
 * Telepathy: The power that allows witches to access the minds of others through spells.
 * Possession: The power to jump one's spirit into the body of another, taking control of said host body.
 * Illusions: The power to alter the senses of others to perceive a false reality.
 * Dream Manipulation: The power to control people's dreams through spells.
 * Resurrection: The power to bring someone or one's self back from the dead.


 * True face: Brandon's true face is revealed when he is about to feed, or heal. The sclera turns blood red, and dark veins form underneath his eyes. Unlike a regular vampires true face, the dark veins form down to his chin. Both underneath his eyes. Brandon's canine teeth extend out into razor sharp fangs, similar to a vampire.

Quadbrid
When Christopher took over Graysons body he mixed the blood of the original lunar vampire, a manticore, and a Leviathan together mixed with black magic he created the first Quadbrid, and the full extent and limits of Grayson's powers are currently unknown. According to Aurelia the extent of Graysons powers could be catastrophic.


 * Super Strength: Grayson is much stronger than immortals, Supernatural Hunters, non-Original vampires, werewolves, Evolved werewolves, non-Original werewolf-vampire hybrids and humans. He is able to decapitate other species with a single chop and shatter windows and doors with small objects. He is even physically superior to the Original vampires, even more so when enraged, using his lunar enhancements, Grayson can easily break the bones of almost any species. Hope and Brandon were able to fight Grayson on equal terms, but neither of them were able to defeat him. While being possessed by Christopher; Graysons strength was almost doubled. In Chapter 9, Hope attacked Grayson, and was able to snap his neck without taking much of a beating. However, in a later chapter, Hope attacked Grayson again, and failed. She originally had the upper hand until Grayson spelled her with a sockwave spell. Graysons strength are also increased with his leviathan half. He could easily fight off Nikolai, a lunar vampire. He was able to break his wrist and neutrialize him almost instantly.
 * Super Speed: Grayson's intensified quickness, agility, reflexes, and endurance makes him much faster than immortals, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, supernatural hunters and humans. He is much faster than his father and other Lunar Vampires. He's faster than Brandon because Grayson is an Original Lunar Vampire. In a later chapter (11/12) Brandon was attacked by Grayson and sped away, Grayson is so much faster than him he was easily able to outrun him and defeat him.
 * Super Agility: Grayson possesses much more superhuman stamina, flexibility, reflexes, agility and dexterity than any immortals, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, and humans, even slightly more than original vampires. He can move, jump very high, flip, climb, and run incredibly fast without difficulty or exhaustion.
 * Super Senses: Grayson has a more enhanced sense of hearing, sight and smell that far exceeds those of any immortals, original vampires, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, and humans.
 * Super Durability: Grayson can take far more trauma than any immortals, original vampires, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids and humans, without much discomfort or injury. However, he has never been dismembered throughout the series, implying that his durability may be close to invincibility though he can still be hurt. Wood and Arsenic Daggers do not weaken him, making him virtually indestructible. Hope casted a cumbustion spell on Grayson, when she sped away, Grayson walked out of the smoke with no damange on his body, however he was quite burned. (this healed almost instantly)
 * Enhanced Healing Factor: The injuries of Grayson heal faster than those of supernatural hunters, Original vampires, non-Original vampires, werewolves, evolved werewolves, non-Original werewolf-vampire hybrids, and humans. He also seems to heal much more quickly when exposed to vervain, a huntresses blood, or wood. He can heal/recover/regenerate from any and all injuries in a matter of seconds. Vervain laced liquid has also been shown to weaken him, though he recovers from the effects much more quickly. Human blood has also known to make the healing process faster. Grayson heals faster than anyone else in the series,  he was shot in heart and dessicated for only minutes; where as when Brandon was killed he revied hours later.
 * Immortality: Since Graysons enhancement, nothing has been shown to be able to kill him; However, it is highly speculated that the Red Oak stake could be able to kill him. Despite the extent of his immortality, Grayson still needs to feed otherwise he will desiccate and become immobile just like any other immortal or vampire-based species. It is only a matter of time before Nature creates a weapon powerful enough to kill him.
 * Day Walking: Due to his Witch heritage, Grayson is immune to the lethal effects that UV rays and sunlight have on vampires thus allowing him to walk in daylight without the use of a daylight ring.
 * Lunar Vampire Bite: Due to Graysons Original Vampire heritage, he has venom which is fatal to non-original vampires, original vampires, and Grayson himself is immune to the venom. His venom also seems to take effect much faster than that of non-original lunar vampires.
 * Lunar Vampire Bite Cure: Grayson's blood seems to be one of the only cures to a lunar vampire bite, this ability seems unique only to Grayson and Brandon.
 * Spell Casting: Due to Graysons' Witch heritage, he is able to cast spells and he has all the same powers of a witch. This includes, but is not limited to: Pyrokenisis, telekinesis, pain infliction, divination, and potion making.
 * Mind Compulsion: Grayson can compel the minds of most sentient creatures; humans, non-Original vampires, and non-Original hybrids. He cannot compel werewolves, evolved werewolves, or any of the other Original vampires.
 * Leviathan Enhancement: Grayson being part Leviathan also Grayson to become much faster and stronger, however his abilities as one are mainly unkown, the full extent of his powers are unknown
 * Manticore Enhancement: Grayson is capable of using his Manticore features to further supplement his powers. He can grow claws and fangs even when he is still in his human form. Grayson can display both sets of vampire and manticore fangs. His eyes also change into those of his manticore form, presumably granting him better eyesight.
 * True Face: Graysons true face is the appearance he is hiding under his normal human face. When Graysons true face is revealed, the sclera of his eyes turns black, and his irises glow a metalic purple, dark veins appear under his eyes as the blood pumps forcefully through him, and his canine teeth extend into razor-sharp fangs. Grayson's true face can be revealed whenever he wishes, but it will appear against his will whenever he is aroused by the scent of blood, or is feeling intense emotions such as anger, lust, sadness, etc. With the fangs come the darkened veins under the eyes as well. Once Grayson killed himself to prevent Brandon from turnin him back into a hybrid, he activated his Original Lunar vampire, and Leviathan side. and the darkened veins used to travel further down to his chin. Similar to a lunar vampire. However since he became a fully completed quadbrid, the darken veins only go to the middle of his face.

Werewolf-vampire hybrid

 * Broken Neck: Breaking a non-Original werewolf-vampire hybrid's neck will result in the non-Original werewolf-vampire hybrid's unconsciousness.
 * The Cure: If a non-Original werewolf-vampire hybrid takes the cure, they will revert back to being a werewolf again. Once taken, the cure prevents them from being immortal again, causing the body to reject vampire blood.
 * Decapitation: Dismembering or removing the head of a non-Original werewolf-vampire hybrid will result in instant death.
 * Desiccation: Being completely drained of blood or the heart-stopping will cause a non-Original werewolf-vampire hybrid to desiccate due to their vampire side, losing most of its strength and any ability to move. This process can be replicated artificially by magic.
 * Heart Extraction: Removing a non-Original werewolf-vampire hybrid's heart will result in instant death.


 * Invitation: Due to their vampire heritage, non-Original werewolf-vampire hybrids are unable to enter a home without an invitation.
 * Magic: Non-Original werewolf-vampire hybrids are susceptible to the powers of witchcraft. This is inclusive of mystical objects such as the Starling Necklace, Gilbert Device, Papa Tunde's Blade, and Dark Objects. A Siphoner can also siphon the magic from a hybrid.
 * Physical Trauma: Minor physical injuries such as gunshots, stab wounds, and broken bones will cause a non-Original werewolf-vampire hybrid pain and also slow them down. However, this is momentary as they will heal completely within seconds. It seems physical trauma can give them pain and weaken them anywhere on the body (ex-eye gauging, drowning).
 * Poison: There are various poisons invented by Dr. Wes Maxfield and Aya, to name a few, that are capable of incapacitating or desiccating a vampire when administered. Klaus also used a poison to kill Tim that not even vampire blood could cure. It is unknown what effect any of these poisons would do if ingested by a non-Original werewolf-vampire hybrid.
 * Vervain: Non-Original werewolf-vampire hybrids are affected by vervain like their non-Original vampire counterparts. They can't compel anyone on vervain.
 * Wolfsbane: Non-Original werewolf-vampire hybrids are affected by wolfsbane like their werewolf counterparts.
 * Wood: Wounding non-Original werewolf-vampire hybrids with a wooden weapon such as wooden bullets will incapacitate for a shorter time than a non-Original vampire.

Lunar Vampire-witch hybrid/ siphoner witch-vampire hybrid

 * Broken Neck: Breaking a non-Original witch-vampire hybrid's neck will result in the witch-vampire hybrid's unconsciousness.
 * The Cure: If a non-Original witch-vampire hybrid takes the cure, they will revert back to being a witch again. Once taken, the cure prevents them from being immortal again, causing the body to reject vampire blood.
 * Decapitation: Dismembering or removing the head of a non-Original witch-vampire hybrid will result in instant death.
 * Desiccation: Being completely drained of blood or the heart-stopping will cause a non-Original witch-vampire hybrid to desiccate due to their vampire side, losing most of it's strength and any ability to move. This process can be replicated artificially by magic.
 * Distraction: Denying a non-Original witch-vampire hybrid from concentrating or giving full attention to their spells, may render them ineffective.
 * Emotions: A non-Original witch-vampire hybrid's magic is subject to the influence of their emotional state and may fluctuate according to them when untrained. According to Sheila Bennett, strong emotions such as worry and anger can fuel a witch's power while emotions such as fear may prevent a witch from properly accessing their powers. This may be made more intense due to a vampire's heightened emotions.
 * Heart Extraction: Removing a non-Original witch-vampire hybrid's heart will result in instant death.
 * Herbs: Ingestion of certain herbs can cause a witch-werewolf hybrid to lose consciousness and prevent them from using magic for an undetermined amount of time. The Lobelia flower prevents concentration and the practice of magic and can be used to weaken a witch-werewolf hybrid as one would weaken a vampire with vervain.
 * Vervain: Due to their vampire aspect, vervain causes a non-Original witch-vampire hybrid to become severely weak and feverish with exposure to or ingestion. Also, If a non-Original witch-vampire hybrid's skin is exposed to vervain, it will burn them. They can't compel anyone on vervain.


 * Huntress' Blood: Consumption of a supernatural huntress' blood will cause a non-Original witch-vampire hybrid to lose their ability to use magic. Prolong exposure poisons them, leading them to get sick and some brands will appear in their body and may eventually lead to death.
 * Hybrid Bloodline: If an Original vampire dies, then all the non-Original witch-vampire hybrids they created will die along with them.
 * Invitation: Due to their vampire heritage, non-Original witch-vampire hybrids are unable to enter a home without an invitation.
 * Magic: Non-Original witch-vampire hybrids are susceptible to the powers of witchcraft. This is inclusive of mystical objects such as the Gilbert Device, Papa Tunde's Blade, and dark objects.
 * Overexertion: If too much power is siphoned from a non-Original witch-vampire hybrid's blood at a time, they may begin to desiccate and ultimately die.
 * Physical Contact: Non-Original witch-vampire hybrids need physical contact with their source in order to siphon from them.
 * Physical Trauma: Minor physical injuries such as gunshots, stab wounds, and broken bones will cause a non-Original witch-vampire hybrid pain and also slow them down. However, this is momentary as they will heal completely within seconds. It seems physical trauma can hurt them anywhere on the body (ex-eye gauging, drowning).
 * Poison: There are various poisons invented by Dr. Wes Maxfield and Aya, to name a few, that are capable of incapacitating or desiccating a vampire when administered. Klaus also used a poison to kill Tim that not even vampire blood could cure. It is unknown what effect any of these poisons would do if ingested by a non-Original werewolf-vampire hybrid.
 * Werewolf Bite: Non-Original witch-vampire hybrids are still susceptible to the bite of a werewolf however, they are able to siphon the magic from the venom, disabling its effects.
 * Wood: Stakes can harm and kill a non-Original witch-vampire hybrid.
 * Cancer: Although vampires cannot catch diseases and illnesses such as cancer, if a human has active cancer and is turned into a vampire, the effects of cancer will increase. The regenerative properties of vampire blood will speed up the replication of cancer cells of and exceed normal stages of the condition. The effects on non-Original witch-vampire hybrids would most likely be affected the same way as non-Original vampires.
 * Zombie Bite: a zombie bite is fatal to a vampire, but a siphon can siphon away the magic from the bite. Rendering it a bite mark.

Original Lunar vampire-witch hybrid

 * Broken Neck: Breaking an original lunar vampire-witch hybrid's neck will result in the Original lunar vampire-witch hybrid's unconsciousness.
 * The Cure: If an original lunar vampire-witch takes the cure, they will revert back to being a witch again. Once taken, the cure prevents them from being immortal again, causing the body to reject vampire blood.
 * Huntress' Blood: Consumption of a supernatural huntress' blood will cause a Original witch-lunar vampire hybrid to lose their ability to use magic. Prolong exposure poisons them, leading them to get sick and some brands will appear in their body. However, Brandon's healing processes is much quicker than that of a non-original vampire and a non-original lunar vampire. A huntresses blood cannot kill Brandon, however their blood hurts Brandon, and will weaken and possibly hinder his magic completely.
 * Desiccation: Being completely drained of blood or the heart-stopping will cause an original lunar vampire-witch hybrid to desiccate due to their vampire side, losing most of it's strength and any ability to move. This process can be replicated artificially by magic.
 * Invitation: Due to their vampire heritage, original lunar vampire-witch hybrids are unable to enter a home without an invitation.
 * Magic: Original lunar vampire-witch hybrids are susceptible to the powers of witchcraft. This is inclusive of mystical objects such as the Starling Necklace, Gilbert Device, Papa Tunde's Blade, Cursed Stake and Dark Objects. It is possible, but equally as unlikely that a Siphoner can also siphon the magic from an original hybrid. even with being a witch, they are still susceptible
 * Physical Trauma: Minor physical injuries such as gunshots, stab wounds, and broken bones will cause an original lunar vampire-witch hybrid pain and also slow them down. However, this is momentary as they will heal completely within seconds. It seems physical trauma can hurt them anywhere on the body (ex-eye gauging, drowning).
 * Poison: There are various poisons invented by Dr. Wes Maxfield and Aya, to name a few, that are capable of incapacitating or desiccating a vampire when administered.
 * Vervain: Vervain prevents an Original lunar vampire-witch hybrid from compelling anyone who takes it and burns them on touch. Original lunar vampire-witch hybrids will heal very quickly from vervain wounds, however.
 * Zombie Bite: A zombie bite is fatal to a vampire. But due to Brandon being an original, this makes him unkillable by the bite. While the bite can still kill Brandon temporarily, he will rise again.
 * Sunlight: Brandon even though he is a hybrid, sunlight still is still harmful to him. He is still burned by sunlight. but this can be migrated by the use of a daylight ring. Although Brandon still burns from the sunlight, he cannot permanently die from this. Being an original Brandon can only be killed by one thing. Sunlight can temporarily kill him, but he will die. He will however light up in fire, and die. But he will awake soon after. Brandon is harmed by sunlight because nature made weaknesses on him due to the fact that he became a witch, without being a siphoner.

Quadbrid

 * Broken Neck: Breaking Grayson's will result in temporary death, though he will revive a short time later.
 * The Cure: If Grayson would take the cure, he would result to becoming a siphon again. However, he could siphon the magic of the cure out of his blood and become immortal again.


 * Desiccation: Being completely drained of blood or the heart-stopping will cause Grayson to desiccate due to their vampire side, losing most of their strength and any ability to move. This process can be replicated artificially by magic.
 * Invitation: Due to their vampire heritage, Grayson is unable to enter a home without an invitation.
 * Magic: Grayson is extremely susceptible to the powers of witchcraft. This is inclusive of mystical and dark objects such as the Loud Shell, red oak stake, etc.
 * Physical Trauma: Minor physical injuries such as gunshots, stab wounds, and broken bones will cause Grayson pain and also slow them down. However, this is momentary as they will heal completely within seconds. It seems physical trauma can hurt them anywhere on the body (i.e. eye gouging, drowning, etc).
 * Vervain: Due to his vamprie heritage, ingesting or coming in contact with vervain will cause buring. Injecting Vervain into his body will cause him to pass out. However his affects of vervain heal much quicker than any other vampire-based species.
 * Leviathan Flower: A leviathan flower, which remains mythical was described by Aurelia as a red flowered stem with white petals, could possibly contain the ability to defeat the first Quadbrid.